TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

Researchers led by the University of California, San Francisco (UCSF), report a new approach that deprived tumors of nutrition in cancer models, and may one day lead to a new approach that can be ...

Tumor growth is associated with profound metabolic and neurochemical alterations, which can lead to the onset of anorexia−cachexia syndrome. Anorexia is defined as the loss of the desire to eat, while ...

In the ongoing effort to find better ways to fight cancer, scientists have developed a creative approach that uses the body’s own fat cells in a surprising way. Instead of allowing tumors to consume ...

Head-and-face DFSP shows a strong predilection for the cheek—where patients are older and fibrosarcomatous variants are rarer—suggesting this distinct distribution pattern can aid earlier, more ...

Patients with triple-negative breast cancer (TNBC) have more aggressive, invasive tumors and fewer treatment options than other kinds of breast cancers. TNBC tumors use fatty acid oxidation as a key ...

Cancer thrives by stealing nutrients. Tumors grow fast because they hijack the body’s resources—especially glucose and fatty acids. But a new study shows there's a way to beat cancer at its own game.

SAN FRANCISCO—The anti-obesity medication tirzepatide, marketed as Mounjaro for diabetes and Zepbound for obesity, reduced obesity-associated breast cancer growth in a mouse model, according to a ...