Repeated head knocks cause long-term damage to the delicate blood-brain barrier, potentially driving chronic traumatic encephalopathy (CTE), a neurodegenerative condition that affects some former ...

Peter Searson is leading a Johns Hopkins University team that is unravelling how Alzheimer's and other diseases disrupt the blood-brain barrier, the complex interface that allows or blocks the passage ...

Our brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and keeping harmful things out, such as bugs that can cause infection and toxins ...

Researchers developed an innovative approach -- demonstrated in mouse models and isolated human brain tissue -- to safely and effectively deliver therapeutics into the brain, providing new ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that ...

Exercise may sharpen the mind by repairing the brain’s protective shield. Researchers found that physical activity prompts the liver to release an enzyme that removes a harmful protein causing the ...

The cells that line the blood vessels in our brains are highly selective. By deciding which molecules are allowed in and out of our most important organ, the barrier these cells form is critical for ...

When a person first exhibits signs of having a stroke, the timing of treatment is critical to restore blood flow to the brain ...

A new study published in the journal Nano Today reveals that nanoplastics, which are tiny plastic particles less than 1 micrometer in size, may cross the blood-brain barrier (BBB). The research marks ...

Manganese is not a metal most people think much about. Unlike lead or mercury, it has a benign reputation. Small amounts of ...

Focused ultrasound with microbubbles is a noninvasive procedure that transiently opens the blood-brain barrier (BBB) using low-intensity sound waves. The openings reseal within 24 hours. Using MRI to ...