The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been employed ...

Researchers have synthesized enhanced vitamin K analogues that outperform natural vitamin K in promoting neuron growth. The ...

New data show additional improvement and stabilization in clinical outcomes in MPS II with 104 weeks of tividenofusp alfa (DNL310) treatment in the open-label, single-arm Phase 1/2 study; sustained ...

The nanoparticles act as tiny engineers of cellular behavior, the researchers explain, orchestrating repair at the molecular ...

From easing tremors to opening the blood-brain barrier, focused ultrasound is emerging as one of medicine’s most promising ...

A UCL-led study shows nanoparticles can restore blood-brain barrier function and clear amyloid-β in mice, reversing Alzheimer ...

It feels like every few months, microplastics are cropping up someplace else they don’t belong: testicles, placentas, carotid artery plaque, lungs. These infinitesimally small plastic particles, which ...

The blood-brain barrier is a natural membrane that protects your brain from toxins and germs. Unfortunately, this barrier also hampers the delivery of important medicines and therapies into the brain.

Gene therapy can be a promising therapy for both genetic and acquired brain disease. However, the limiting problem in brain gene therapy is delivery to the brain followed by regulation of the ...

The findings, demonstrated in mouse models and isolated human brain tissue, could expand treatment options for neurological and psychiatric diseases. (Nanowerk News) Scientists at the Icahn School of ...

Merging biophysics with knowledge of how the brain handles waste led to an impressive 50 percent reduction of amyloid beta in ...

Nanomedicine. 2012;7(8):1225-1233. Most of the strategies described for the passage of drugs across the BBB can be enhanced by nanotechnology and some of the mechanisms involved include: NPs open the ...