For the first time, scientists have solved the high-resolution structure of the molecular transporter TSPO, which introduces cholesterol into mitochondria. This protein also serves as a docking site ...
Cholesterol is an important regulator of membrane protein function. However, the exact mechanisms involved in this process are still not fully understood. Here we study how the tertiary and quaternary ...
A study could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization. A new ...
In 1985, the Nobel Prize in Physiology or Medicine was awarded to Michael Brown and Joseph Goldstein for identifying the receptor that clears LDL particles from the bloodstream. High blood levels of ...
Export of LDL-derived cholesterol from lysosomes requires the cooperation of the integral membrane protein Niemann–Pick C1 (NPC1) and a soluble protein, Niemann–Pick C2 (NPC2). Mutations in the genes ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 5 (Mar. 4, 2003), pp. 2512-2517 (6 pages) Niemann-Pick disease type C2 (NP-C2) is a fatal hereditary ...
4 University of Canberra, Research Institute for Sport and Exercise (UCRISE) Canberra, Australian Capital Territory, Australia Background Tendon pain occurs in individuals with extreme cholesterol ...
A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback