Researchers discovered a kinase-driven phosphorylation switch that activates DNA packaging machinery, aligning nucleosomes at ...

A study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior. Chromatin, the compact form of DNA, not only packages genetic material but also ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

A recent study has shed light on the transcriptional regulatory mechanisms of Penicillium expansum, the fungal culprit behind blue mold disease in fruits. By mapping chromatin accessibility at ...

AMES, Iowa – In their long strings of nucleotides, DNA molecules hold massive troves of genetic data providing instructions for how living organisms should function – the blueprint of life. How the ...

Some of the signs of aging in human cells originate in the cell nucleus, because the packaged form of DNA changes with age.

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...