Structural biologists at the University of Wisconsin-Madison today published cryo-electron microscopy structures of the complete bacterial DNA replication restart complex — a molecular machine that le ...
As DNA strands ravel and unravel in an intricate dance, one notable event takes center stage: replication. This process is essential to life, but the finer details of its orchestrated steps are still ...
If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...
Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide ...
From the first unzip of the double helix to the final joining of DNA fragments, replication is a carefully coordinated process. Understanding it helps explain how life preserves its genetic code with ...
Researchers at The University of Texas MD Anderson Cancer Center have identified a key enzyme—RNase H2—that helps ...