First reported in 1928 by Otto Diels and Kurt Alder, the Diels-Alder reaction is one of the most relevant transformations in organic chemistry. Its capacity to generate six-membered rings enables the ...
The Diels–Alder reaction has been widely used in synthetic organic chemistry since its discovery in 1928. The catalyst-free nature, functional group tolerance and high efficiency of the Diels–Alder ...
When it comes to catalysis, chemists have nothing on nature’s enzymes, which get reactions to go smoothly and stereoselectively under the mildest of conditions. Now, taking the “if you can’t beat them ...