Researchers at Spain’s CNIO have mapped 20,000 distinct DNA repair “scars,” building the first human REPAIRome. This atlas ...
“[...] this suggests a model where the accumulation of DNA damage with aging impairs vascular function ultimately resulting in [cardiovascular disease].” Advanced ...
When an SSB appears, polymerase epsilon approaches the nick before retracing its steps thanks to its exonuclease, allowing fork reversal to take place. The nick is repaired as an SSB, and replication ...
Francesca Storici consults at Tessera Therapeutics. She has received funding from the National Institutes of Health and the National Science Foundation. Your DNA is continually damaged by sources both ...
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