Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Most people do not use one drug, but many. SUDs often involve different substances, but the underlying problem is really one ...

Just weeks prior to his death, Brandon Clarke was arrested for possession of kratom. The NBA player allegedly had nearly half ...

Kratom and 7-OH may be marketed as herbal supplements, but they function like opioids — shaping how clinicians treat ...

SINCE they first arrived five years ago around four million of us have taken the “miracle” GLP-1 fat jabs. By the end of 2026 ...

An experimental medication was shown to achieve strong pain relief in early studies without the risks associated with typical opioids. The finding comes from the National Institute on Drug Abuse (NIDA ...

Opium is a highly addictive drug. It’s made from juice extracted from the unripe seed pods of opium poppy plants (the scientific name is Papaver somniferum). Opium is used to make a class of drugs ...

To learn more about our editorial approach, explore The Direct Message methodology. A class of drugs designed to manage blood sugar and shrink waistlines appears to be doing something researchers say ...

Many of the prescription drugs that are commonly abused or misused are brands most people have heard of. Painkillers, also known as opioids, are the most frequently abused ones, per data from the New ...

People taking new weight-loss drugs say they curb cravings for booze, drugs, and nicotine. Did scientists inadvertently create an addiction-busting drug? Scientific evidence is mounting that the new ...