Neuronal specification, expansion and differentiation are tightly regulated by the concerted actions of transcription and chromatin modifying factors that are recruited to regulatory elements in the ...

Salk researchers have identified a new set of molecules that fuel the growth of tumors in pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer. The new research findings ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

A comprehensive analysis has identified novel enhancers associated with neuronal development and disease. An international collaboration of researchers led by Masahito Yoshihara at Chiba University ...

(L to R) Corresponding author Brian Abraham, PhD, and co-first authors Kelsey Maher, PhD, and co-first author Jie Lu, PhD, all of the St. Jude Department of Computational Biology. Cells express ...