Cell culture is vital to many biological fields, including oncology, immunology, drug discovery, genomics, and cell biology. Researchers depend on accurate cell enumeration to maintain healthy ...

A new study has found that MET (hepatocyte growth factor receptor) signaling plays a critical protective role in acetaminophen-induced acute liver failure (ALF). This pathway is shown to work as a ...

Proper storage of CPHs is vital to ensure that they maintain their features. Cells should be stored below -150 °C in liquid nitrogen vapor. Cells stored in liquid nitrogen may cause liquid to enter ...

Differentiated hepatocyte organoids formed networks of small canals that allowed bile acid to pass, in a manner similar to human tissue. While organoids aim to mimic human organs, the liver’s ...

Data obtained from the in vitro investigation of test compounds is crucial for effectively extrapolating in vivo ADMET/DMPK characteristics. In vitro studies like these offer researchers essential ...

In a new study, researchers from Institute of Science Tokyo, Japan, have utilized bile acids as farnesoid X receptor agonists to develop unique hepatic organoids that are capable of sustained, ...