Heterochromatin, sometimes known as the “dark side of the genome,” is a poorly studied fraction of DNA that makes up about half of our genetic material. For more than 50 years scientists have puzzled ...
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🧬 A fallen architect of DNA through evolution
In an article published in the journal Nature Communications, scientists have studied a protein, called HP1, which is ...
The human AF10 gene has been associated with chromosomal translocation in acute leukemias. In the March 15 EMBO Reports, Linder et al. describe their study of the Drosophila AF10 homolog, dAF10, in an ...
Mechanistic model for G9a-H3K9me2 in preserving centromere integrity. G9a-mediated H3K9me2 at centromeres prevents the invasion of H3K9me3 into core centromeric domains, which ensures proper ...
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