DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...
Researchers identify a novel centromere-specific histone H3 variant called the “CENP-A”, which reconstituted with H4 forms “CENP-A–H4” octasome and explore its role in mitosis. Centromeres, ...
A research team led by Dr. Xiang David Li, Associate Professor from the Department of Chemistry, in collaboration with Dr. Karen Wing Yee Yuen from the School of Biological Sciences and Dr. Jason Wing ...
Researchers identify hundreds of candidate histone proteins in bacteria, including one with an unusual way of binding to DNA. Now, Warnecke and colleagues are challenging the idea that these ...
The biology of histone proteins encompasses their synthesis in the cytosol, nuclear import and incorporation into nucleosomes, as well as subsequent eviction from chromatin, redeposition, storage or ...
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