As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...

A gene called DNMT3A is important for guiding blood stem cells into forming all the cell types present in blood, including red blood cells, white blood cells and platelets. When this gene accumulates ...

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes) and is ...

A research team from the University of California (UC), Irvine, has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. The ...

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

Artios Pharma collected $115 million from an oversubscribed series D that will support its growing ambitions for its pipeline of DNA damage response (DDR)-targeting cancer prospects. The biotech is ...

COPENHAGEN — Most people associate sunburns with DNA damage — it’s what we’ve been taught in textbooks and by dermatologists for years. However, surprising new research suggests that it’s actually RNA ...