A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...
Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.
"Although more extensive studies are required to better understand the functional significance of TAS2Rs in cancer cells, we suggest that intracellular TAS2Rs act as chemosensory receptors that drive ...
Researchers at the University of North Carolina (UNC) at Chapel Hill School of Medicine have revealed the detailed structure of the bitter taste receptor, a protein called TAS2R14, and have shown ...
Morning Overview on MSN
Scientists watch drug molecules hit cell receptors in real time
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, ...
Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.
Histamine is widely known for its role in allergic reactions but also functions as a key neurotransmitter in the brain, where ...
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