Lung cancer is the second-most common cancer and the leading cause of cancer death in the United States. Over 80% of lung cancers are non-small cell lung cancers, in which tumor cells are larger and ...

Each year, more than 3 million people are diagnosed with cancers driven by mutations in three RAS-family genes: KRAS, NRAS, and HRAS. RAS-family mutations are associated with numerous types of cancer.

Roughly a quarter of all cancerous tumors are caused by mutations in the KRAS gene, which fosters cell growth. For more than three decades, scientists believed these mutations were impervious to ...

Responsible for nearly 10 million deaths worldwide in 2020, cancer consistently ranks among the leading causes of death each year. Brought on by genetic mutations and external risk factors, cancer is ...

KRAS was long thought undruggable in cancer until scientists discovered a hidden binding pocket in mutant KRAS, leading to targeted therapies. In this discussion, Asfar S. Azmi, associate professor of ...

When cancer-driving proteins resist various treatments, Northwestern University scientists have uncovered a new solution. Don’t fight them — throw them in the cellular trash. In a new study, ...

Inside every human cell, proteins are constantly being tagged with small chemical modifications after they're produced. Known ...

CURE spoke with Dr. Alexander Spira to learn what patients need to know about the KRAS G12C mutation and its treatment strategies. Knowledge of the KRAS G12C mutations can be very important for ...