Phosphatidate phosphatase (PAP) enzymes play a pivotal role in lipid metabolism, acting as a control point that directs metabolic flux between membrane phospholipid synthesis and the production of ...
Pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) are produced in large quantities locally in the joints and subsequently enter the bloodstream. TNF-α and IL-6 may promote LDL metabolism by ...
AD is associated with significant changes in genes related to neuroinflammation, and lipids are crucial in this metabolic dysregulation. Abnormal phospholipid accumulation in the brain not only ...
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