Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC). This ...
Phosphatidate phosphatase (PAP) enzymes play a pivotal role in lipid metabolism, acting as a control point that directs metabolic flux between membrane phospholipid synthesis and the production of ...
Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year. This ...
AD is associated with significant changes in genes related to neuroinflammation, and lipids are crucial in this metabolic dysregulation. Abnormal phospholipid accumulation in the brain not only ...
Hoth Therapeutics, Inc. (NASDAQ: HOTH), a clinical-stage biopharmaceutical company focused on developing innovative therapies for patients with unmet medical needs, today announced new female-specific ...
Mutations in the lipid transporter ABCA7 are known to elevate the risk of Alzheimer’s disease, but how they do so has been murky. Now, scientists led by Li-Huei Tsai at MIT in Cambridge, Massachusetts ...
The frequency of driver mutations in non-small cell lung cancer patients: The Turkish nation-wide, observational, Registurk-Lung study (updated analysis). Clinical analysis of AFFINITY trial: ...
Cancer Center at Illinois (CCIL) members Ratnakar Singh and Michael Spinella collaborated in new research that fills in ...
Lipid nanoparticles consist of spherical vesicles made of ionizable lipids with a positive charge at a low pH level, while being neutral at a physiological pH. Such a characteristic enables RNA ...
Using state-of-the-art microscopy techniques, researchers have shed new light on the underlying mechanisms driving Alzheimer's disease. Alzheimer's disease causes significant problems with memory, ...
Researchers at UC San Diego have deployed state-of-the art imaging techniques to discover the metabolism driving Alzheimer’s disease; results suggest new treatment strategies Alzheimer’s disease ...
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