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Oral cancer pain and opioid tolerance share a common EGFR mechanism
Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 16 (April 19, 2022), pp. 1-10 (10 pages) Allosteric modulators of G-protein-coupled receptors (GPCRs) ...
LOS ANGELES, CA - January 15, 2026 - PRESSADVANTAGE - Muse Treatment Alcohol & Drug Rehab Los Angeles has released ...
Naloxone, also known by the brand name Narcan, is one of the most important drugs in the United States’ fight against the opioid crisis. It reverses an opioid overdose nearly instantly, restarting ...
Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due ...
Research findings suggest opioids, with varying efficacy at the μ and κ receptors, produce independent effects on unique pain mechanisms and individual responsiveness for some is dependent on pain ...
Opioid use and abuse is a significant social, health and economic issue in Canada. Researchers at the University of Calgary's Faculty of Veterinary Medicine (UCVM) and Hotchkiss Brain Institute (HBI) ...
The illegal use of synthetic opioids such as fentanyl and its analogues has killed tens of thousands of people and wreaked devastation on families across the United States. Indeed, in 2017, the White ...
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