Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic variations ...

UT researchers have developed the first viable alternative to a 75-year-old method for sequencing proteins. Image of amino acids, the building blocks of proteins. Scientists at The University of Texas ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions. Consisting of amino acids strung together into peptide chains, these ...

A team of researchers has built a new protein sequencing workflow that pairs mirror proteases with deep learning software to read peptide sequences with far greater accuracy than previous methods.

In 1997, Sanger, Nicklen and Coulson described a method for determining DNA nucleotide sequences. 1 Nearly five decades later, Sanger sequencing remains an entrenched technology for targeted ...

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...