Oligodendrocytes (OLs) differentiate to myelinate central nervous system (CNS). CNS myelination by OLs is important not only for saltatory conduction of action potentials but also for trophic support ...

University of Alabama at Birmingham researchers, for the first time ever, have achieved patch-clamp studies of an elusive part of mammalian myelinated nerves called the Nodes of Ranvier. At the nodes, ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...

A team has shown that the axons of auditory neurons in the brainstem which respond to low and high-frequency sounds differ in their morphology, and that these variations correlate with differences in ...

William M. Spees, Tsen-Hsuan Lin, Peng Sun, Chunyu Song, Ajit George, Sam E. Gary, Hsin-Chieh Yang, Sheng-Kwei Song Proceedings of the National Academy of Sciences of the United States of America, Vol ...

Although myelination largely occurs during early postnatal life, myelinating oligodendrocytes are still generated in the adult brain. Myelin turnover in the adult is necessary for proper neuronal ...