Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 5 (Jan. 30, 2007), pp. 1522-1527 (6 pages) Knowing gene structure is vital to understanding gene function ...

We propose a fast and powerful analysis algorithm, titled Modelbased Analysis of Tiling-arrays (MAT), to reliably detect regions enriched by transcription factor chromatin immunoprecipitation (ChIP) ...

DNA chip technology has changed the way we think about examining gene expression. It relies on our ability to stick small pieces of DNA with defined sequences at precise locations on a silicon chip.

Traditional computational methods for predicting gene number integrate information from numerous sources, such as sequence signatures of gene structure, similarity to genes in other organisms and ...

Array-based comparative genomic hybridization (aCGH) has revealed copy-number variations (CNVs) to be the cause of MR. 6, 7, 8 Although Tarpey et al. 4 screened for mutations in the coding regions of ...