The NHS has highlighted the dangers of long-term tramadol use, including hyperalgesia. This condition, which can make ...

Tramadol, a commonly prescribed opioid for moderate-to-severe pain, may offer only limited relief while carrying significant risks, especially with long-term use. This article explores what tramadol ...

Extended-release formulations of tramadol hydrochloride (tramadol ER) (multiple brands) may provide an alternative treatment option for reducing withdrawal symptoms in patients with opioid use ...

Guidance from the NHS highlights that some people who take tramadol over an extended period of time may find that they become ...

The data showed patients receiving buprenorphine (90.3%) were significantly more likely to be retained at the end of the taper vs. patients receiving clonidine (66.1%) but retention with tramadol ER ...

A randomized clinical trial compared tramadol extended-release with clonidine and buprenorphine for the management of opioid withdrawal symptoms in patients with opioid use disorder in a residential ...

Opioids, such as oxycodone, morphine, codeine, tramadol and fentanyl, are commonly prescribed to manage pain. You might be ...

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David Juurlink is the head of the Division of Clinical Pharmacology and Toxicology, Department of Medicine, at the University of Toronto. The patient was a man in his early 60s. A year and a half ...