Isaac Brown rushed for 130 yards and a touchdown before leaving late with a leg injury and Keyjuan Brown scored twice in the second half to lift No. 16 Louisville to a 28-16 victory over Virginia Tech.

After several close ACC wins this season for unbeaten Georgia Tech, the dam finally broke defensively during Saturday night's 48-36 loss at NC State, the second stunner in conference play to highlight Week 10 following SMU's overtime triumph over Miami.

Only a quartet of contests remain for Virginia Tech football in its 2025 campaign. Through a turbulent campaign, the Hokies have notched three wins and will need to claim as many over the next month to qualify for a bowl game this season.

Virginia Tech is trying to hire head coach James Franklin before two other college football jobs likely open before 2026.

The No. 7 Yellow Jackets (8-1, 5-1 ACC) also are no longer in first place in the ACC standings after the loss, falling behind No. 15 Virginia (8-1, 5-0), who defeated California 31-21 to move to 5-0 in conference play this season.

Georgia Tech became the second undefeated team to lose its first game of the season on Saturday after Navy lost at North Texas and joined No. 9 Vanderbilt and No. 10 Miami with losses in Week 10. Just four undefeated teams remain with four weeks to go in the regular season: Ohio State, Indiana, Texas A&M and BYU.

Why did Virginia Tech football's Brent Pry era not work out and what should the Hokies look for in a new coach? As VT's coaching search approaches November with a crowded 2025-26 FBS carousel, 247Sports surveyed established high school coaches from the region.

With the matchup a couple days away, we have our first inclination as to who could play, and will not. On Thursday, the ACC released the first availability report for Louisville's matchup vs. Virginia Tech. An updated report will come out at 8:00 p.m. EST on Friday, and a final report will then be released two hours before kickoff.