EurekAlert!

Single-cell RNA sequencing (scRNA-seq) identified four clusters of human embryonic eye lens cell clusters. (IMAGE)

(A) Schematic diagram of the human embryonic eyes design. (B) The uniform manifold approximation and projection (UMAP) algorithm was used to group the fetal lens scRNA-seq data into four clusters, ...
EurekAlert!

Belgian scientists create a scRNA-seq atlas of the multiple myeloma immune microenvironment across disease stages

Brussels, 12 November 2024 - Multiple Myeloma (MM) is an incurable blood cancer, leading to weakened immunity, bone damage, and other serious health issues. The high relapse rates following initial ...

High-performance cell atlas workflow driven by manifold fitting

Researchers from the National University of Singapore (NUS) have developed CellScope, a high-performance single-cell analysis ...
GEN

Potential ALS Mitochondrial Target Identified with CRISPR, scRNA-seq

Eleven years after the Ice Bucket Challenge brought ALS into the public spotlight, the neurodegenerative disease is once again drawing scientific attention—this time through the lens of CRISPR and ...
GEN

Systemic Sclerosis Organ Damage Revealed Through scRNA-Seq

Systemic sclerosis (SSc) is a rare autoimmune disease that can harden the skin, impair blood flow, and damage internal organs such as the lungs and kidneys. But no two patients experience the disease ...
HealthTech

Perturb-Seq in Practice: Dissecting Gene Function with CRISPR + scRNA-Seq

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...