Course TopicsPower analyses and sample size calculations are important parts of many research projects. Often, before data are even collected, it is necessary to calculate and justify the required ...

Our sample size formula includes several existing formulas as special cases when the working variance function is correctly specified as the true variance function. We also consider a sensitivity ...

Some notes on the behaviour of sample size calculations and power for unequal group sizes This information was omitted from the video and so is included here as text. In many scenarios the ratio of ...

Formal sample size calculation can help us think through what patient-based research can and cannot tell us about medicine.

For a desired power of detecting the association between a disease and several potential risk factors in case-control studies, Yang (1978, Biometrika 65, 635-640) and Halperin (1980, Biometrika 67, ...