With the cessation of development and support of Perian, Mac users will eventually need to find a new way to play many otherwise unsupported video file formats. With choices including NicePlayer, ...

Users have reported issues playing back some MP4 that are encoded using QuickTime with high quality in iTunes 6.0.4. One reader writes: ...

Also, with this process you can avoid the conversion time of burning subtitles in the video with Quicktime or Perian: you can just use Subler to mux the .srt file. Overall, Subler is the best solution ...