Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the ...

Regulatory T cells help your immune system distinguish between ‘self’ and ‘nonself’ – and can open doors to better treatments for cancer, autoimmune disease and transplant rejection.

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi discovered cells that protect the body from autoimmune diseases.

The function of the ORPs is determined both by their differential lipid exchange modes and by privileged localization at the ER/PM subdomains. These findings reveal a role of PtdSer as a signaling ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. CD8 + T cells have critical roles in tumor ...