Demi Moore, who is nominated for Best Actress at the 2025 Oscars, and Margaret Qualley, who plays a younger version of Moore's character in Coralie Fargeat's horror film 'The Substance,' each put their bodies on the line for the demanding shoot.

Demi Moore thought her four-decade Hollywood career might be over a few years ago. The actress, 62, battled negative thoughts about herself after a producer dismissed her as a "popcorn actress."

He thinks her performance had substance. Dennis Quaid, who starred in the 2025 Oscar-nominated film “The Substance” with Demi Moore and Margaret Qualley, is confident that Moore will win big at the Academy Awards on Sunday.