ALZFORUM2d
Sex Differences in Blood of Alzheimer’s and Parkinson’s Patients
Sex Delta by Cell Type. In men with Alzheimer’s (top left), B cells (red boxes) were fewer (blue), while NK cells (blue boxes ...
ALZFORUM2d
Can Autoimmunity Spark Alzheimer’s Disease?
Autoimmunity and Alzheimer’s. People with autoimmune disorders in the UCSF (left) and Stanford medical systems (right) were ...
ALZFORUM2d
In Amyloidosis, Ephrin-A4 Goads Astrocytes to Massacre Synapses
Erythropoietin-producing hepatoma (Eph) receptors, including EphA4, are expressed on the cell surface and involved in brain development, which involves extensive pruning of synapses. A variant in ...
ALZFORUM3d
Fragments of Tau’s Microtubule Binding Region Mess with Synapses
The fragments also directly compromise synapses they encounter along the way, according to a preprint posted February 24 on bioRxiv. Specifically, tau fragments containing the microtubule binding ...
ALZFORUM3d
With Age, Macrophages Chew up the Blood-CSF Barrier
The blood-CSF barrier has been far less studied than the blood-brain barrier. Scientists have detected age-related changes in ...