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  1. Restless legs syndrome - Symptoms and causes - Mayo Clinic

    Feb 25, 2025 · Restless legs syndrome can begin at any age and tends to get worse with age. It can disrupt sleep, which interferes with daily activities. RLS also is known as Willis-Ekbom disease. …

  2. Restless Legs Syndrome (RLS): Causes, Symptoms & Treatment

    Restless legs syndrome (RLS) is a brain, nerve and sleep condition that causes a strong, nearly irresistible urge to move your legs that’s at least partially relieved by movement.

  3. Restless Leg Syndrome: Causes, Home Remedies, and More

    Jun 27, 2025 · More often than not, the cause of RLS is a mystery. There may be a genetic predisposition and an environmental trigger. More than 40 percent of people with RLS have some …

  4. Restless Legs Syndrome - National Institute of Neurological Disorders ...

    Apr 7, 2025 · RLS is a sleep disorder triggered by resting and attempting to sleep. It is also a movement condition, as people with RLS are forced to move their legs to find relief from symptoms. People with …

  5. Restless legs syndrome - Wikipedia

    Restless legs syndrome (RLS), also known as Willis–Ekbom disease (WED), is a neurological disorder, usually chronic, that causes an overwhelming urge to move one's legs. [2][10] There is often an …

  6. Restless Legs Syndrome: Symptoms, Causes, and Treatments

    Aug 29, 2025 · Causes: The causes and risk factors of RLS include family history, iron deficiency, brain chemical imbalance, pregnancy, older age, and other health conditions like kidney disease and …

  7. Restless Legs Syndrome (RLS) - Johns Hopkins Medicine

    Some cases are believed to be inherited. Some cases have been linked with nerve damage in the legs from diabetes, kidney problems, iron deficiency, certain medicines, pregnancy, sleep disorders, and …

  8. Restless leg syndrome: Potential causes and triggers

    Dec 20, 2024 · Most cases of restless leg syndrome have no known cause. However, researchers associate certain genetic variants with the condition. It may also occur due to a disruption of …

  9. What causes restless leg syndrome and how can I stop the nighttime ...

    Jul 9, 2025 · Restless leg syndrome (RLS) happens when low brain dopamine, reduced iron in the spinal cord, certain genes, pregnancy-related iron shifts, kidney disease or medications overstimulate the …

  10. Restless Legs Syndrome (RLS): Causes, Symptoms & Treatments

    Jul 19, 2024 · Restless legs syndrome (RLS) is a nervous system disorder that causes an overpowering urge to move your legs. It’s also known as Willis-Ekbom disease, primary RLS, or idiopathic RLS....