Class I Antidysrhythmic Therapy (Sodium Channel Blockers): Video, Causes, & Meaning | Osmosis
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32 reactions | Stephen G. Waxman, M.D., Ph.D., explains how blocking the Nav1.8 sodium channel can help reduce pain without adverse effects. Full episode: https://nej.md/itt-ep14 Learn more about this concept in an editorial authored by Dr. Waxman: https://nej.md/44U8v58 | The New England Journal of Medicine | Facebook
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Journavx is a recently FDA-approved non-opioid oral pain medication for adults with moderate-to-severe acute pain. It works by selectively blocking the NaV1.8 sodium channel in peripheral pain-sensing nerves — reducing pain signals before they reach the central nervous system. It’s the first new oral pain drug class in over 20 years and was approved for short-term postoperative and injury-related pain. Clinical trials showed significant pain reduction after surgeries like abdominoplasty and buni
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